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Vitamin B12 Boosts Cell Reprogramming Efficiency

Researchers at IRB Barcelona discover that vitamin B12 significantly boosts the efficiency of cellular reprogramming, thus holding promise for regenerative medicine.
Cell structure.
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Molecular Glue Degraders Could Target “Undruggable” Proteins

Cells contain molecular machinery that targets and disposes of unwanted proteins. Scientists would like to hijack this process to control proteins involved in cancer and other diseases, using a type of molecule called a molecular glue degrader.
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3D Genome Folding Helps Preserve Identity When Cells Divide

A new MIT study proposes a theoretical model that helps explain how cellular memory is passed from generation to generation when cells divide.
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Hormone Therapy May Be Potential Treatment for Liver Fibrosis

Researchers have discovered previously unknown changes in a specific type of liver cells, potentially opening avenues for a new treatment for liver fibrosis, a potentially life-threatening condition.
Close up view of the stem cell sorting chip.
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Novel Microfluidic Method Optimizes Stem Cell Extraction for Advanced Cell Therapies

Traditional bone marrow aspirate (BMA) stem cell extraction methods are complex, time-consuming, and yield poor results due to antiquated centrifugation techniques.
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New Insights Into DNA Repair Pathway Implicated in Breast, Ovarian and Prostate Cancers Revealed

A lesser-known DNA repair pathway that is upregulated in breast, ovarian and prostate cancer has been pieced together and laid out step by step in a new paper.
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Improved Research Models for Parkinson’s Disease Created

Researchers developed an improved method to study Parkinson’s disease in the lab. Along the way, researchers also uncovered clues that may help scientists figure out how to detect Parkinson’s earlier and point the way toward better treatments.
Macrophages infiltrating a tumor spheroid.
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Inability of Macrophages To Penetrate Tumors Could Explain Cell Therapy Failures

Macrophages, a type of white blood cell that can destroy invading pathogens, have an innate ability to infiltrate tumor cells, making them a potentially important tool in treatments that use transplanted cells to fight disease, known as cell therapy.
People running.
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Daily Scheduled Exercise Helps To Sync Body Clock

Physical activities in the morning, associated with daily patterns of sleep/wake cycle, convey timing information from the light-sensitive central clock in the brain to the weight-bearing skeletal tissues.
Two robotic hands holding a pen and a water bottle.
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Printing Robots With Bones, Ligaments, and Tendons

For the first time, researchers have succeeded in printing a robotic hand with bones, ligaments and tendons made of different polymers using a new laser scanning technique.
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