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 Drug-resistant, Mycobacterium tuberculosis bacteria.
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Cancer Immunotherapy Shows Promise Against Tuberculosis

A promising new cancer therapy also appears extremely potent against one of the world’s most devastating infectious diseases: tuberculosis (TB). Scientists found the therapy dramatically reduces TB growth, even for bacteria that are drug-resistant.
A silvery-gray strand of DNA.
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Genomic "Tug of War" Could Influence How Cancer Patients Respond to Decitabine

A genomic tug of war for a gene activator could explain why some cancers respond to decitabine and others don't respond or become resistant over time.
A strand of DNA that looks like it's falling apart.
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New Insights Into DNA Repair Pathway Implicated in Breast, Ovarian and Prostate Cancers Revealed

A lesser-known DNA repair pathway that is upregulated in breast, ovarian and prostate cancer has been pieced together and laid out step by step in a new paper.
Macrophages infiltrating a tumor spheroid.
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Inability of Macrophages To Penetrate Tumors Could Explain Cell Therapy Failures

Macrophages, a type of white blood cell that can destroy invading pathogens, have an innate ability to infiltrate tumor cells, making them a potentially important tool in treatments that use transplanted cells to fight disease, known as cell therapy.
Blue and red fluorescence microscopy of pancreatic cancer cells.
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Experimental Drug Obstructs Tumor Migration in Pancreatic Cancer

Researchers have identified the genetic changes that occur during pancreatic cancer metastasis and have found a drug to disrupt the process.
Double helix structure of DNA.
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“DNA Loops” in Pediatric Brain Tumors Double Relapse Risk

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA are twice as likely to relapse and three times as likely to die within five years of diagnosis.
A strand of DNA shown in blue.
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Disrupting One Gene in CAR T Cells Makes Them More Potent

Disrupting one gene in CAR T cells used for cancer therapy makes them more potent and able to fight the cancer for longer, reports a new study.
Immunofluorescence imaging of the bone marrow.
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Contents of Human Bone Marrow Mapped

A team of researchers has mapped the location and spatial features of blood-forming cells within human bone marrow, providing a powerful way to study diseases like sickle cell anaemia and leukemia.
Artistic representation of the gene clusters that influence cancer progression.
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4,749 Key Gene Clusters Influence the Progression of 32 Different Cancer Types

Researchers have released a groundbreaking study identifying 4,749 key gene clusters, termed “prognostic modules,” that significantly influence the progression of 32 different types of cancer.
Cancer cells.
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Cancer Stem Cells Trigger Macrophage Aging

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.
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