Neurodegeneration – Webinars and Online Events

Dr. Walker will discuss how he integrates proteomic, genetic, brain imaging and cerebral spinal fluid biomarkers from initially cognitively normal individuals who later develop dementia, in order to discover novel blood-based biomarkers and mechanistically relevant proteins for therapeutic target prioritization.

bit.bio’s first-of-its-kind precision cellular reprogramming technology, opti-ox™, addresses the limitations of lot consistency, cell definition and scalability by controlling the precise expression of cell-fate determining genetic factors.

We will introduce the National Institutes of Health (NIH) Center for Alzheimer’s and Related Dementias (CARD) long-read sequencing initiative, which will generate a new genetic resource for Alzheimer’s and related dementias from thousands of human brain samples.

In this webinar, Dr. Roberts will highlight how his work aims to identify disease-specific lipid isomers that can be used for the early detection and diagnosis of PD, using ion mobility mass spectrometry.

Alzheimer’s disease is the most common form of neurodegenerative disease, estimated to contribute to 60–70% of all cases of dementia worldwide. Increasing evidence suggests that neuroinflammation, primarily mediated by microglia, contributes to the onset and progression of Alzheimer’s disease.

In order to generate a genomic atlas of protein levels in neurologically relevant tissues, Dr. Carlos Cruchaga and his team profiled thousands of proteins, and performed bioinformatic analyses to determine if any of the identified proteins are drugable.

In this webinar, our expert speaker, Professor Lei Liu, Assistant Professor of Neurology from Harvard Medical School will discuss strategies in developing an ultrasensitive immunoassay* to measure oligomeric amyloid β in human plasma precisely.

In this webinar, Dr. Kim Ekroos explains how an HRIM-MS technique based on structures for lossless ion manipulation (SLIM) technology is enabling him to dissect the metabolic glycosphingolipid map in Parkinson’s disease.

In this webinar, Dr. Nathan Basisty will introduce a new computational tool – TurnoveR – which accurately calculates protein turnover rates from mass spectrometry analysis of metabolic labeling experiments. He will also demonstrate how this technology derives new biological insights into age-related diseases.