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Unlocking the Potential of Cancer Immunotherapy with 3D Immune Cell Killing Assays

Unlocking the Potential of Cancer Immunotherapy with 3D Immune Cell Killing Assays
Credit : Istock

CAR T-cell therapies have shown impressive results in treating hematological malignancies. However, developing specialized therapies for the treatment of solid tumors still remains a challenge.

3D cell culture models are essential in researching how therapies can infiltrate and remain effective in solid tumor microenvironments. By optimizing 3D cell killing assays using the latest analysis/analytical technologies, researchers can guide and accelerate the engineering of novel therapeutics. 

This literature review explores a range of successful assay setups that leverage different analytical technologies.

Download this literature review to discover:

  • Different assay setups for 3D killing assays
  • High-content analysis, image cytometry and in vivo imaging for 3D killing assays
  • Benefits and challenges of the different technologies  

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