Improving Peptide Annotation and Glycan Localization Using EAD

Glycoproteins are gaining special recognition in proteomics thanks to their multiple roles in biological processes, be it as biopharmaceuticals or as disease biomarkers in pathological processes. The bottom-up analysis of glycopeptides therefore offers important advantages for glycoprotein characterization, providing information about the structure and composition of the glycans and about the carrier protein.

In this webinar, our expert speakers will discuss how to optimize glycopeptide analysis using capillary liquid chromatography coupled to tandem mass spectrometry, showcasing how the ZenoTOF 7600 system enhances the analysis of proteins and their post-translational modifications.

Attend this webinar to: 

• Learn how to design an LC-MS/MS experiment that optimizes acquisition parameters for glycan analysis
• Discover the importance of all steps in the workflow, including peak picking and search parameters during data processing
• Explore how improved parameters boost the annotation of glycopeptides