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Latest Articles

Illustration of plasmid DNA being dispensed from a pipette tip onto a cell culture for transfection.
Article

An Introduction to Transfection, Transfection Protocol and Applications

In this article, we discuss the fundamentals of transfection, provide an overview of some of the commonly employed methods and a sample protocol. Finally, we consider some of the key applications of transfection.
A gloved hand holds a section of DNA in metal tweezers, which has come out of a DNA helix.
Article

Cutting With CRISPR: Assessing Safety as Technology Moves Into the Clinic

The Nobel Prize winning CRISPR-Cas genome editing technology is being adopted for a wide variety of research applications. In this article, we will explore what these applications are and outline the progress of CRISPR methodologies in recent years, in addition to current bottlenecks in CRISPR research and how we can look to address them.
Scientist using a manual pipette.
Article

Why Are Manual Pipettes Still So Popular?

Electronic pipettes offer several benefits, but many laboratories are still resistant to making the switch from manual options. This article discusses how equipping your team with electronic pipettes could rapidly pay for itself.

A pregnant woman stands over a cot.
Article

Do Cesarean-Born Babies “Miss Out” on Essential Microbes?

Much research has focused on the gut microbiome, but we also carry microbes in other bodily parts, including the respiratory tract, skin and genitalia. How do other microbiomes, beyond the gut, develop during infancy, and can factors such as delivery method affect their development? Technology Networks interviewed Dr. Wouter de Steenhuijsen Piters to find out.
Returning genetic ancestry results to participants of the Afromexico Genomics Project.
Article

Leveling the Field in Ancient DNA Research

Some stories of history are written in ink, and others are written in nucleotide bases. Ancient DNA (aDNA) analysis – the study of DNA from archaeological or paleontological specimens – is perhaps the closest scientists will ever come to a time machine – a window into the past. In this feature article, we explore how inclusion and representation are critical considerations when we look through that window.
Gloved hand holding a slightly open blood agar Petri dish of bacteria up to a computer screen displaying a protein structure.
Article

Understanding Structural Biology, Its Applications and Creating a Molecular Model

In this article, we consider what structural biology tells us and the techniques used to investigate it, the role of computation and how techniques can be used together to answer questions in a range of application areas.
Human immunodeficiency virus-1 virions in the process of budding from a cultured lymphocyte.
Article

Viral Evolution: Changing Priorities Under Environmental Cues

This article will highlight some of the selective pressures that can shape viral evolution, focusing on human parainfluenza virus (HPIV) and human immunodeficiency virus (HIV).
Representation of DNA nitrogen-containing bases.
Article

Next-Generation Sequencing in Precision Oncology: Detecting Minimal Residual Disease

The development of next-generation sequencing (NGS) has made the sequencing of patient tissues or tumors a realistic option and has allowed for the rapid development of personalized cancer treatments. This article explores how NGS is being used in precision oncology to detect minimal residual disease.
A scientist holds a chunk of brain with tweezers.
Article

Building an Atlas of the Brain To Guide Neuroscience: An Interview With the Allen Institute's Ed Lein

A new project to map the billions of cells in the human brain is underway. The project, dubbed BICAN (BRAIN Initiative Cell Atlas Network) will exploit rapid advances in genomic and cellular technology to build an atlas of the brain. Technology Networks spoke to project lead Ed Lein to find out more.


A hand holds a glass containing ice and amber-colored liquid.
Article

How Does Alcohol Affect the Brain and the Body?

Alcohol has complex, unseen and far-reaching effects at the molecular and cellular level, including altering our gut microbiome, accelerating the aging process and even changing the synapses in the brain.
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