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Latest App Notes & Case Studies

Oligos with Confidence
App Note / Case Study

Characterize Your Oligos With Confidence

Custom oligo synthesis can result in the formation of impurities. Hence, final products must be characterized to ensure they meet quality assurance and control standards.
Precision Oligo Sequencing
App Note / Case Study

A Simplified Method for Precise Oligo Sequencing

LC/MS methods can be used to analyze a wide range of oligo samples. However, ion-pairing reagents can interfere with analyses and present challenges in multi-use systems.
Antigen
App Note / Case Study

Fast Track Antigen-Specific B- and T-Cell Discovery

This application note demonstrates how Single Cell Immune Profiling and Barcode Enabled Antigen Mapping (BEAM) can be used to profile thousands of hPBMCs from a single donor.

CAR T: A Promising Cell Therapy for Cancer Treatment content piece image
App Note / Case Study

CAR T: A Promising Cell Therapy for Cancer Treatment

CAR-T cell therapy has emerged as one of the most promising novel treatments in the fight against cancer.
Integrating Laboratory Equipment Into Computerized Systems content piece image
App Note / Case Study

Integrating Laboratory Equipment Into Computerized Systems

Laboratory Information Management Systems (LIMS) is becoming increasingly important in GMP regulated environments in order to ensure data integrity and faster working practices.
Understanding the Hidden Value of Quality content piece image
App Note / Case Study

Understanding the Hidden Value of Quality

Outsourcing quality management activities can save biomanufacturers time, money and resources. It can support scientists in bringing life-changing therapeutics to market swiftly and efficiently.
 Transitioning From RUO to cGMP for Clinical Trials content piece image
App Note / Case Study

Transitioning From RUO to cGMP for Clinical Trials

Both RUO and cGMP compliance play important roles in the drug discovery pipeline. However, meeting regulatory demands can be a challenge when accelerating new drugs to the clinic.
Discover an Automated Workflow for Precise Metabolite Identification content piece image
App Note / Case Study

Discover an Automated Workflow for Precise Metabolite Identification

Discover an automated processing workflow that utilizes both EAD and CID data for the most confident characterization of pharmaceutical drug metabolites.
Metabolic Preconditioning For Improved CAR-T Cell Therapy content piece image
App Note / Case Study

Metabolic Preconditioning for Improved CAR-T Cell Therapy

Metabolism is a key driver of CAR-T cell fitness and function. Hence, metabolic preconditioning methods can enhance the bioenergetic capacity of CAR-T cells in culture, supporting their persistence and antitumor activity
Highly Sensitive Mass Spectrometry Methods for Quantifying PROTACs content piece image
App Note / Case Study

Highly Sensitive Mass Spectrometry Methods for Quantifying PROTACs

Protein-targeting chimeras (PROTACs) have gained significant attention recently due to their high potency in nanomolar drug concentrations and target selectivity. However, low test concentrations in complex matrices present analytical challenges.
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